Obstetric Outcomes of SARS-CoV-2 Infection in Asymptomatic Pregnant Women

Cruz-Lemini, Monica and Ferriols Perez, Elena and de la Cruz Conty, Maria and Caño Aguilar, Africa and Encinas Pardilla, Maria and Prats Rodríguez, Pilar and Muner Hernando, Marta and Forcen Acebal, Laura and Pintado Recarte, Pilar and Medina Mallen, Maria and Perez Perez, Noelia and Canet Rodriguez, Judit and Villalba Yarza, Ana and Nieto Velasco, Olga and del Barrio Fernandez, Pablo and Orizales Lago, Carmen and Marcos Puig, Beatriz and Muñoz Abellana, Begoña and Fuentes Ricoy, Laura and Rodriguez Vicente, Agueda and Janeiro Freire, Maria and Alferez Alvarez-Mallo, Macarena and Casanova Pedraz, Cristina and Alomar Mateu, Onofre and Lesmes Heredia, Cristina and Wizner de Alva, Juan and Posadas San Juan, Alma and Macia Badia, Montserrat and Alvarez Colomo, Cristina and Sanchez Muñoz, Antonio and Pratcorona Alicart, Laia and Alonso Saiz, Ruben and Lopez Rodriguez, Monica and Barbancho Lopez, Maria and Meca Casbas, Marta and Vaquerizo Ruiz, Oscar and Moran Antolin, Eva and Nuñez Valera, Maria and Fernandez Fernandez, Camino and Tubau Navarra, Albert and Cano Garcia, Alejandra and Soldevilla Perez, Susana and Gattaca Abasolo, Irene and Adanez Garcia, Jose and Puertas Prieto, Alberto and Ostos Serna, Rosa and Guadix Martin, Maria and Catalina Coello, Monica and Espuelas Malon, Silvia and Sainz Bueno, Jose and Granell Escobar, Maria and Cruz Melguizo, Sara and Martinez Perez, Oscar (2021) Obstetric Outcomes of SARS-CoV-2 Infection in Asymptomatic Pregnant Women. Viruses, 13 (1). p. 112. ISSN 1999-4915

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Abstract

Around two percent of asymptomatic women in labor test positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Spain. Families and care providers face childbirth with uncertainty. We determined if SARS-CoV-2 infection at delivery among asymptomatic mothers had different obstetric outcomes compared to negative patients. This was a multicenter prospective study based on universal antenatal screening for SARS-CoV-2 infection. A total of 42 hospitals tested women admitted for delivery using polymerase chain reaction, from March to May 2020. We included positive mothers and a sample of negative mothers asymptomatic throughout the antenatal period, with 6-week postpartum follow-up. Association between SARS-CoV-2 and obstetric outcomes was evaluated by multivariate logistic regression analyses. In total, 174 asymptomatic SARS-CoV-2 positive pregnancies were compared with 430 asymptomatic negative pregnancies. No differences were observed between both groups in key maternal and neonatal outcomes at delivery and follow-up, with the exception of prelabor rupture of membranes at term (adjusted odds ratio 1.88, 95% confidence interval 1.13–3.11; p = 0.015). Asymptomatic SARS-CoV-2 positive mothers have higher odds of prelabor rupture of membranes at term, without an increase in perinatal complications, compared to negative mothers. Pregnant women testing positive for SARS-CoV-2 at admission for delivery should be reassured by their healthcare workers in the absence of symptoms.

Item Type: Article
Uncontrolled Keywords: SARS-CoV-2; pregnancy; coronavirus; asymptomatic infection; perinatal outcomes; delivery; maternal complications
Subjects: e-Archives > Medical Science
Depositing User: Managing Editor
Date Deposited: 27 Dec 2022 05:30
Last Modified: 01 Jul 2024 09:08
URI: http://ebooks.abclibraries.com/id/eprint/146

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